GIST Support WikiThis page is for information related to AZD2171, one of the Clinical Trial Drugs. Feel free to add your own experiences with the drug in the comments section or any other links to useful resources.
[edit] Basic Information
Manufacturer: AstraZeneca International
Molecular Targets: VEGF receptors (VEGFR1, VEGFR2, VEGFR3), as well as KIT and (less potently) PDGFRA and PDGFRB
Trials: Phase I trial in the United Kingdom: [1] link here
GIST Support International website page: [2] link here
[edit] Comments from Trial Participants
31 Mar 2007
Subject: Drug Trial AZD 2171
My brother in law here in the UK has been told about a new drug trial AZD 2171. He was diagnosed with GIST in the winter of 2003 tried Gleevec for two years and then in Feb 2006 went on to Sutent. Is AZD 2171 at present in use in America if so is there anybody on this forum who knows about it and can let me know of its sucess?
Response: As far as I know it is ONLY in trial in the UK. Here is our page on this drug. This has everything I know... http://www.gistsupport.org/treatments/emerging-treatments/inhibitors-of-kit-pdgfr-or-vegf/azd2171.php