Log in / create account

GIST Support Wiki

This will take you to the page you typed to the left. If it does not exist, you will have the opportunity to create it and will be shown search results for similar pages.

This searches the titles and content of the wiki pages for the term you typed.

Edit
History

Clinical Trial Drugs

This page links to other pages with information on drugs in various stages of clinical trials. If you have any information that you would like to share with the community, please add your knowledge on the page for the appropriate drug. As always, patients are advised to seek the advice of their GIST specialist when determining which clinical trials are best suited for their individual needs.

Contents

1 Inhibitors of KIT, PDGRF and VEGF
2 HSP90 (Heat Shock Protein 90) Inhibitors
3 PI3K Inhibitor
4 Drugs in Combination
5 Pre-Trial Drugs / New Ideas / Miscellaneous

[edit] Inhibitors of KIT, PDGRF and VEGF

Nilotinib (Tasigna) - formerly AMN107.

Sorafenib (Nexavar) - formerly BAY 43-9006

Dasatinib (Sprycel) - formerly BMS-354825

MLN518

Vatalanib (PTK787)

OSI-930

AZD2171

XL-820

[edit] HSP90 (Heat Shock Protein 90) Inhibitors

IPI-504

17AAG

CNF1010

CNF2024

SNX-5422

STA-9090

BIIB021

[edit] PI3K Inhibitor

BEZ235

XL765

BGT226

[edit] Drugs in Combination

Gleevec and Sutent

Genasense and Gleevec

Perifosine and Gleevec

Perifosine and Sutent

Flavopiridol and Doxorubicin

Bevacizumab (Avastin) and Gleevec

Bevacizumab (Avastin) and Sutent

Nexavar and Rapamune

[edit] Pre-Trial Drugs / New Ideas / Miscellaneous

800mg Gleevec vs. 37.5mg Sutent after progression on 400mg Gleevec

Molecular Profiling Trial

MP470/AXL Kinase

SAHA (Suberoylanilide Hydroxamic Acid) with Flavopiridol

OSI-817

Miscellaneous

Retrieved from "http://gistsupport.medshelf.org/Clinical_Trial_Drugs"