I've tolerated the 340mg dose fine, but unfortunately my Alkaline Phosphatase shot up to 500. So I'm off the drug after 7 days.
I started Crenolanib Jan. 5. I had to stop Jan. 12 due to elevated Alkaline Phosphatase. I restarted Jan. 19 after my Alk Phos had fallen back to 2.5 times normal. Yesterday it had fallen a little more, even after being back on crenolanib, so I'm still on medicine for another week. Hopefully it will be clear sailing from here.
I think my pleural effusion is slowly worsening, but they don't seem overly concerned. My restaging CT will be in 5 weeks.