The medical term for puffy eyes is "periorbital edema" and this is an extremely common Gleevec side effect.
[edit] Prescription Treatments
Some patients are prescribed diuretics such as Lasix for water retention, including puffy eyes.
[edit] Non-prescription Approaches
A caffeine-containing eye cream helps reduce the puffiness. There are numerous eye creams with caffeine on the market-they are marketed to reduce morning puffiness. I tried Loreal Eye Defense -about 15 minutes before makeup.
Salt really puffs my eyes up badly. I TRY to watch the salt content of things but it's everywhere!
Try Avon eye serum.
Tea tree stick (looks like lipstick, only light green in color) from the neighborhood health food store.
My husband has been on Gleevec for four weeks and has eye swelling and I started giving him green tea, cranberry juice, cucumber and celery. All are natural diuretics. It worked great.
See our general Edema page also.